Annandale contains a great variety of scenery. The old wool town of Moffat is the capital of the upper dale, with the spectacular Grey Mare's Tail waterfall thundering down from the highest summits in the area, and offering some of the finest hillwalking country in southern Scotland. Further south the River Annan flows through a broad and fertile strath; Lochmaben is notable for its fine lochs, whilst the town of Lockerbie lies just to the east. The town of Annan guards the outflow of the river into the Solway Firth.
East of Annandale lies Eskdale. The Samye Ling Tibetan Centre - the most important Buddhist site in Britain - lies near the lonely head of this dale. Further down is the fine old town of Langholm - the Muckle Town. Langholm offers an array of fine walks.